Nodal disease predicts recurrence whereas other traditional factors affect survival in a cohort of South African patients with differentiated thyroid carcinoma

Table 3 Univariate analyses for CS survival

Variable	N	10-year CS survival %	p-value (log rank)	Prognostically unfavourable subgroup
Age
Less than 25	27	100	0.01*	56–65
26–35	44	90	0.002*
36–45	52	98	0.003*
46–55	40	94	0.03*
56–65*	41	72
66–75	23	86
Greater than 76	4	45
Age
< 45	116	97	< 0.001	≥ 45
≥ 45	115	80
Gender
Male	42	95	ns	–
Female	189	91
T stage
T0	1	100		T4
T1^Ϯ*	53	98		and
T2^Ϯ*	79	100		TX
T3^#*	53	77
T4	25	71	< 0.01^Ϯ 0.018^#
TX	20	65	< 0.01*
Extra-thyroid extension
No^Ϯ	184	98	< 0.001*	Extra-thyroid
Yes*	31	76		extension and
Unknown	16	59	< 0.001 ^Ϯ	unknown
Pathology
Follicular and Hurthle	90	82		Follicular and
Papillary	140	95	0.012*	Hurthle
Nodal status
N0^Ϯ	147	96		NX
N1	67	89
NX (unknown)	17	70	0.001^Ϯ
Residual tumour
R0/1^Ϯ	179	99		R2, n/a
R2	20	61	< 0.001^Ϯ	and
n/a	18	56	< 0.001^Ϯ	unknown
Unknown	14	85	< 0.001^Ϯ
Metastases
M0	203	96	0.001*	M1
M1*	23	54
MX (unknown)	5	67
Post-operative risk stratification for risk of recurrence
High*	44	46
Intermediate	98	91	< 0.001*	High
Low	82	96	< 0.001*
Unknown	7	80

ISSN: 2059-7347