Table 1 Characteristics of the study population
Variable, p-value of chi-squarea | No. (%) | ||
|---|---|---|---|
Total (n = 1015) | ECE Negative (n = 611) | ECE Positive (n = 404) | |
Age, p = 0.609 | |||
 ≤54 | 226 (22.3) | 140 (22.9) | 86 (21.3) |
 55–64 | 264 (26.0) | 151 (24.7) | 113 (28.0) |
 65–74 | 234 (23.0) | 139 (22.8) | 95 (23.5) |
 ≥75 | 291 (28.7) | 181 (29.6) | 110 (27.2) |
Sex, p = 0.009 | |||
 Female | 324 (31.9) | 214 (35.0) | 110 (27.2) |
 Male | 691 (68.1) | 397 (65.0) | 294 (72.8) |
Race, p = 0.273 | |||
 White | 853 (84.0) | 508 (83.1) | 345 (85.4) |
 Black | 80 (7.9) | 52 (8.5) | 28 (6.9) |
 Hispanic | 46 (4.5) | 25 (4.1) | 21 (5.2) |
 Asian/Pacific Islander | 27 (2.7) | 21 (3.4) | 6 (1.5) |
 Other/Unknown | 9 (0.9) | 5 (0.8) | 4 (1.0) |
Charlson/Deyo Score, p = 0.815 | |||
 0 | 809 (79.7) | 491 (80.4) | 318 (78.7) |
 1 | 156 (15.4) | 91 (14.9) | 65 (16.1) |
 ≥2 | 50 (4.9) | 29 (4.8) | 21 (5.2) |
Pathologic T Stage, p < 0.001 | |||
 1 | 134 (13.2) | 101 (16.5) | 33 (8.2) |
 2 | 246 (24.2) | 167 (27.3) | 79 (19.6) |
 3 | 347 (34.2) | 192 (31.4) | 155 (38.4) |
 4 | 288 (28.4) | 151 (24.7) | 137 (33.9) |
Pathologic N Stage, p < 0.001 | |||
 1 | 373 (36.8) | 296 (48.4) | 77 (19.1) |
 2 | 633 (62.4) | 312 (51.1) | 321 (79.5) |
 3 | 9 (0.9) | 3 (0.5) | 6 (1.5) |
Grade, p = 0.001 | |||
 Low | 64 (6.3) | 48 (7.9) | 16 (4.0) |
 Intermediate | 191 (18.8) | 130 (21.3) | 61 (15.1) |
 High | 590 (58.1) | 328 (53.7) | 262 (64.8) |
 Unknown | 170 (16.8) | 105 (17.2) | 65 (16.1) |
Surgical Margins, p < 0.001 | |||
 Negative | 553 (54.5) | 363 (59.4) | 190 (47.0) |
 Positive | 462 (45.5) | 248 (40.6) | 214 (53.0) |
Histology, p = 0.736 | |||
 Squamous Cell | 368 (36.3) | 219 (35.8) | 149 (36.9) |
 Non-Squamous Cell | 647 (63.7) | 392 (64.2) | 255 (63.1) |
Radiotherapy, p = 0.003 | |||
 Not Administered | 232 (22.9) | 159 (26.0) | 73 (18.1) |
 Administered | 783 (77.1) | 452 (74.0) | 331 (81.9) |
Chemotherapy, p < 0.001 | |||
 Not Administered | 675 (66.5) | 451 (73.8) | 224 (55.4) |
 Administered | 340 (33.5) | 160 (26.2) | 180 (44.6) |