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Table 2 Multivariate analysis of factors associated with survival

From: Extracapsular extension is not a significant prognostic indicator in non-squamous cancers of the major salivary glands

Variables

Squamous Cell

Non-Squamous Cell

Hazard Ratio

p-value

Hazard Ratio

p-value

Age

 ≤54

1 [Reference]

–

1 [Reference]

–

 55–64

1.105

0.778

1.313

0.154

 65–74

1.353

0.377

1.467

0.054

 ≥75

2.342

0.006

2.165

< 0.001

Sex

 Female

1 [Reference]

–

1 [Reference]

–

 Male

0.987

0.949

1.051

0.723

Race

 White

1 [Reference]

–

1 [Reference]

–

 Black

0.871

0.768

1.162

0.443

 Hispanic

1.908

0.113

0.462

0.091

 Asian/Pacific Islander

2.007

0.148

0.386

0.184

 Other/Unknown

0.000

1.000

1.628

0.351

Charlson/Deyo Score

 0

1 [Reference]

–

1 [Reference]

–

 1

1.406

0.093

1.430

0.046

 ≥2

1.569

0.153

2.395

0.001

Pathologic T Stage

 1

1 [Reference]

–

1 [Reference]

–

 2

1.798

0.070

1.583

0.127

 3

1.791

0.059

2.998

< 0.001

 4

2.781

0.001

3.268

< 0.001

Pathologic N Stage

 1

1 [Reference]

–

1 [Reference]

–

 2

1.403

0.077

1.261

0.144

 3

0.876

0.897

0.565

0.443

Grade

 Low

1 [Reference]

–

1 [Reference]

–

 Intermediate

1.090

0.824

1.554

0.320

 High

0.719

0.389

2.786

0.009

 Unknown

0.617

0.306

2.471

0.028

Surgical Margins

 Negative

1 [Reference]

–

1 [Reference]

–

 Positive

1.350

0.086

1.093

0.505

Radiotherapy

 Not Administered

1 [Reference]

–

1 [Reference]

–

 Administered

0.559

0.005

0.622

0.003

Chemotherapy

 Not Administered

1 [Reference]

–

1 [Reference]

–

 Administered

0.779

0.236

1.309

0.064

ECE Status

 Negative

1 [Reference]

–

1 [Reference]

–

 Positive

1.449

0.042

1.000

0.998